New compounds from the aerial parts of Calligonum mongolicum

Previously undescribed compounds, (R)-4-(4-hydroxyphenyl)-2-butanol 2-O-(6-O-galloyl)-β-D-glucopyranoside (1) and (E)-5-(4-hydroxyphenyl)pent-2-enoic acid (2), together with 20 known compounds (3-22) were isolated from the aerial parts of Calligonum mongolicum. Compound 3 was obtained a natural source for first time, all (1-22) reported time in this plant. The structural elucidation 1 2 performed mainly by HRFABMS, HREIMS, 1H 13C NMR, 1H–1H COSY, HMQC, HMBC spectroscopy. Some enzyme inhibitory activities estimated, catechin (7) showed ten times higher phenoloxidase activity (IC50 9.1 μM) than epicatechin (8) 148.3 μM). Compounds 7 8 have common molecular structure, except their stereochemistry, result supported reproducibility test using pure guaranteed authentic samples.